Article
Soluble P-selectin and vascular endothelial growth factor in steady state sickle cell disease: relationship to genotype.
Journal of thrombosis and thrombolysis - 1 Apr 2008
Blann A D, Mohan J S, Bareford D, Lip G Y H
Abstract excerpt
Sickle cell disease (SCD) is characterised by abnormal coagulopathy and angiogenesis although their relationships in two common genotypes, homozygous (HbSS) SCD and sickle-haemoglobin C disease (HbSC), are unexplored. We measured markers of platelet activation (soluble P-selectin [sP-selectin]), fibrinolysis (D-dimer) and angiogenesis (vascular endothelial growth factor [VEGF]) in 27 HbSS patients, 37 HbSC...
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