Article
P-selectin gene genotypes or haplotypes and cardiovascular complications in type 2 diabetes mellitus.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Sept 2006
Zalewski G, Ciccarone E, Di Castelnuovo A, Zito F, Capani F, de Gaetano G, Donati M B, Iacoviello L
Abstract excerpt
BACKGROUND AND AIM: Increased levels of sP-selectin, a member of the selectin family involved in the transient attachment of leukocytes to endothelial cells, are found in a number of conditions including diabetes and ischemic heart disease. A number of polymorphisms in the gene encoding P-selectin have been identified. The purpose of the present study was to explore the role of three non-synonymous P-selectin...
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