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Article

Platelet P-selectin and platelet mass, volume and component in sickle cell disease: relationship to genotype.

Thrombosis research - 1 Jan 2006

Mohan J S, Lip G Y H, Bareford D, Blann A D

Abstract excerpt

BACKGROUND AND PURPOSE: Excess platelet activation (e.g. increased soluble P selectin [sPsel] and beta thromboglobulin [beta-TG]) is well established in sickle cell disease (SCD) and may contribute to the prothrombotic/hypercoagulable state and vascular occlusion characteristic of the disease. We hypothesised altered whole platelet P-selectin (pPsel), and morphological platelet indices mass, volume and component...

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Source

Identifiers

PMID: 16051315
DOI: 10.1016/j.thromres.2005.05.010

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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