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Article

P-selectin gene haplotypes modulate soluble P-selectin concentrations and contribute to the risk of venous thromboembolism.

Thrombosis and haemostasis - 1 May 2008

Ay Cihan, Jungbauer Lea V, Kaider Alexandra, Koder Silvia, Panzer Simon, Pabinger Ingrid, Mannhalter Christine

Abstract excerpt

The cell adhesion molecule P-selectin mediates the interaction of activated platelets or endothelial cells with leukocytes. In arterial and venous thromboembolism (VTE) increased soluble P-selectin (sP-selectin) concentrations have been found, and associations of P-selectin genotypes with thrombotic disease have been proposed. We assessed the effect of four single nucleotide polymorphisms (SNPs) [one in the...

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PMID: 18449419
DOI: 10.1160/TH07-11-0672

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SELP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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P-selectin gene haplotypes modulate soluble P-selectin concentrations and contribute to the risk of venous thromboembolism.PMID 18449419Read ↗

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