Article
RhoA activation by CNFy restores cell-cell adhesion in kindlin-2-deficient keratinocytes.
The Journal of pathology - 1 Jul 2014
He Yinghong, Sonnenwald Tanja, Sprenger Adrian, Hansen Uwe, Dengjel Joern, Bruckner-Tuderman Leena, Schmidt Gudula, Has Cristina
Abstract excerpt
Kindlins are a family of integrin adapter and cell-matrix adhesion proteins causally linked to human genetic disorders. Kindlin-2 is a ubiquitously expressed protein with manifold functions and interactions. The contribution of kindlin-2 to integrin-based cell-matrix adhesions has been extensively explored, while other integrin-independent roles emerge. Because of the early involvement of kindlin-2 in...
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