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Article

A gene-brain-cognition pathway for the effect of an Alzheimer׳s risk gene on working memory in young adults.

Neuropsychologia - 1 Aug 2014

Stevens Benson W, DiBattista Amanda M, William Rebeck G, Green Adam E

Abstract excerpt

Identifying pathways by which genetic Alzheimer׳s disease (AD) risk factors exert neurocognitive effects in young adults are essential for the effort to develop early interventions to forestall or prevent AD onset. Here, in a brain-imaging cohort of 59 young adults, we investigated effects of a variant within the clusterin (CLU) gene on working memory function and gray matter volume in cortical areas that support...

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Source

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Identifiers

PMID: 24967550
DOI: 10.1016/j.neuropsychologia.2014.06.021
PMCID: PMC4337824

Genes

CLU
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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