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Article

An Alzheimer's Disease Genetic Risk Score Predicts Longitudinal Thinning of Hippocampal Complex Subregions in Healthy Older Adults.

eNeuro - 1 Jan 2000

Harrison Theresa M, Mahmood Zanjbeel, Lau Edward P, Karacozoff Alexandra M, Burggren Alison C, Small Gary W, Bookheimer Susan Y

Abstract excerpt

Variants at 21 genetic loci have been associated with an increased risk for Alzheimer's disease (AD). An important unresolved question is whether multiple genetic risk factors can be combined to increase the power to detect changes in neuroimaging biomarkers for AD. We acquired high-resolution structural images of the hippocampus in 66 healthy, older human subjects. For 45 of these subjects, longitudinal 2-year...

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Identifiers

PMID: 27482534
DOI: 10.1523/ENEURO.0098-16.2016
PMCID: PMC4945997

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APOE
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PICALM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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