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Article

Pooled genotyping of microsatellite markers in parent-offspring trios.

Genome research - 1 Jan 2000

Kirov G, Williams N, Sham P, Craddock N, Owen M J

Abstract excerpt

We studied the extent to which genotyping of simple sequence repeat polymorphisms (SSRs) in pooled DNA samples can be used to predict differences in allele frequencies between parents and their affected offspring. We also developed a simple method of correction for the effects of stutter and differential amplification on the analysis of SSRs in pooled DNA samples based on widely available software. We genotyped...

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PMID: 10645955
PMCID: PMC310506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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