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Article

Rapid evolution of piRNA-mediated silencing of an invading transposable element was driven by abundant de novo mutations.

Genome research - 1 Apr 2020

Zhang Shuo, Pointer Beverly, Kelleher Erin S

Abstract excerpt

The regulation of transposable element (TE) activity by small RNAs is a ubiquitous feature of germlines. However, despite the obvious benefits to the host in terms of ensuring the production of viable gametes and maintaining the integrity of the genomes they carry, it remains controversial whether TE regulation evolves adaptively. We examined the emergence and evolutionary dynamics of repressor alleles after...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32238416
DOI: 10.1101/gr.251546.119
PMCID: PMC7197473

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