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Article

Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample.

Environmental research - 1 Aug 2014

Lind Lars, Penell Johanna, Syvänen Anne-Christine, Axelsson Tomas, Ingelsson Erik, Morris Andrew P, Lindgren Cecilia, Salihovic Samira, van Bavel Bert, Lind P Monica

Abstract excerpt

Several of the polychlorinated biphenyls (PCBs), i.e. the dioxin-like PCBs, are known to induce the P450 enzymes CYP1A1, CYP1A2 and CYP1B1 by activating the aryl hydrocarbon receptor (Ah)-receptor. We evaluated if circulating levels of PCBs in a population sample were related to genetic variation in the genes encoding these CYPs. In the population-based Prospective Investigation of the Vasculature in Uppsala...

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Identifiers

PMID: 24926919
DOI: 10.1016/j.envres.2014.05.017
PMCID: PMC5562272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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