Article
Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p'-dde levels in a population-based sample.
Environment international - 1 Jan 2017
Lind Lars, Ng Esther, Ingelsson Erik, Lindgren Cecilia, Salihovic Samira, van Bavel Bert, Mahajan Anubha, Lampa Erik, Morris Andrew P, Lind P Monica
Abstract excerpt
OBJECTIVES: Since the metabolism of the organochlorine pesticide dichlorodiphenyltrichloroethane (DDT) is not fully known in humans, we evaluated if circulating levels of a major breakdown product of DDT, p,p'-DDE, were related to genome-wide genetic and methylation variation in a population-based sample. METHODS: In the population-based Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS)...
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