Article
Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample.
Environmental research - 1 Jul 2015
Ng Esther, Salihovic Samira, Lind P Monica, Mahajan Anubha, Syvänen Anne-Christine, Axelsson Tomas, Ingelsson Erik, Lindgren Cecilia M, van Bavel Bert, Morris Andrew P, Lind Lars
Abstract excerpt
BACKGROUND: Polychlorinated biphenyls (PCBs) are a group of man-made environmental pollutants which accumulate in humans with adverse health effects. To date, very little effort has been devoted to the study of the metabolism of PCBs on a genome-wide level. OBJECTIVES: Here, we conducted a genome-wide association study (GWAS) to identify genomic regions involved in the metabolism of PCBs. METHODS: Plasma levels...
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