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Article

Relationships among CYP2B6 genetic variants and serum levels of multiple polychlorinated biphenyls and hydroxylated metabolites in a Japanese population.

Journal of hazardous materials - 15 Mar 2025

Lyu Zhaoqing, Kobayashi Hatasu, Iwase Kodai, Haraguchi Koichi, Fujii Yukiko, Harada Kouji H

Abstract excerpt

Production of polychlorinated biphenyls (PCBs) has been banned since 2001 but health risks from exposure persist. PCBs are metabolized by cytochrome P450 enzymes, including CYP2B6. However, the link between CYP2B6 gene polymorphisms and PCB metabolisms is poorly characterized. This study investigated the relationships among serum levels of major indicator PCBs and hydroxylated PCBs (OH-PCBs), which are PCB...

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Share to Cytochrome P-450 CYP2B6
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39724708
DOI: 10.1016/j.jhazmat.2024.136953

Genes

CYP2B6

Variants

Provenance

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