Article
Cytochrome P4501A1 genotypes and smoking- and hypertension-related ischemic stroke risk.
Human & experimental toxicology - 1 May 2013
Demirdöğen B Can, Adali A Ç, Bek S, Demirkaya Ş, Adali O
Abstract excerpt
This study aimed to determine whether the coding (A4889G) and noncoding region (T6235C) polymorphisms of the gene coding for cytochrome P4501A1 (CYP1A1), a xenobiotic-metabolizing enzyme responsible for the metabolism of carcinogenic polycyclic aromatic hydrocarbons, are involved in the pathogenesis of ischemic stroke in Turkish population. Study group consisted of 226 ischemic stroke patients and 113 controls....
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