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Article

Genetic polymorphisms in CYP1A1 and GSTM1 predispose humans to PCBs/PCDFs-induced skin lesions.

Chemosphere - 1 May 2006

Tsai Pei Chien, Huang Wenya, Lee Yeu-Chin, Chan Shih Huang, Guo Yueliang Leon

Abstract excerpt

INTRODUCTION: Polychlorinated biphenyls (PCBs) and dibenzofurans (PCDFs) are ubiquitous persistent pollutants in humans. Whether people with different genotypes are with different susceptibility to these chemicals are unknown. In a group of people highly exposed to PCBs/PCDFs, we tested the hypothesis that genotypic polymorphisms affected susceptibility for development of skin manifestations. METHODS: In 1979,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16580705
DOI: 10.1016/j.chemosphere.2005.08.012

Genes

GSTM1
GSTT1

Provenance

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