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Article

A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry.

Journal of human genetics - 1 Mar 2011

Kral Brian G, Mathias Rasika A, Suktitipat Bhoom, Ruczinski Ingo, Vaidya Dhananjay, Yanek Lisa R, Quyyumi Arshed A, Patel Riyaz S, Zafari A Maziar, Vaccarino Viola, Hauser Elizabeth R, Kraus William E, Becker Lewis C, Becker Diane M

Abstract excerpt

A 58 kb region on chromosome 9p21.3 has consistently shown strong association with coronary artery disease (CAD) in multiple genome-wide association studies in populations of European and East Asian ancestry. In this study, we sought to further characterize the role of genetic variants in 9p21.3 in African American individuals. Apparently healthy African American siblings (n = 548) of patients with documented CAD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21270820
DOI: 10.1038/jhg.2010.171
PMCID: PMC3079521

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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