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Article

Timed deletion of Twist1 in the limb bud reveals age-specific impacts on autopod and zeugopod patterning.

PloS one - 1 Jan 2014

Loebel David A F, Hor Angelyn C C, Bildsoe Heidi K, Tam Patrick P L

Abstract excerpt

Twist1 encodes a transcription factor that plays a vital role in limb development. We have used a tamoxifen-inducible Cre transgene, Ubc-CreERT2, to generate time-specific deletions of Twist1 by inducing Cre activity in mouse embryos at different ages from embryonic (E) day 9.5 onwards. A novel f...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24893291
DOI: 10.1371/journal.pone.0098945
PMCID: PMC4044014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24893291-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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