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Article

Generation of a Twist1 conditional null allele in the mouse.

Genesis (New York, N.Y. : 2000) - 1 Sept 2007

Chen You-Tzung, Akinwunmi Peter O, Deng Jian Min, Tam Oliver H, Behringer Richard R

Abstract excerpt

Twist1 is the mouse ortholog of TWIST1, the human gene mutated in Saethre-Chotzen syndrome. Previously, a Twist1 null allele was generated by gene targeting in mouse embryonic stem cells. Twist1 heterozygous mice develop polydactyly and a craniofacial phenotype similar to Saethre-Chotzen patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17868088
DOI: 10.1002/dvg.20332

Genes

TWIST1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17868088-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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