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Article

Methyltransferase G9A Regulates Osteogenesis via Twist Gene Repression.

Journal of dental research - 1 Sept 2017

Higashihori N, Lehnertz B, Sampaio A, Underhill T M, Rossi F, Richman J M

Abstract excerpt

Here we investigate the role of epigenetic factors in controlling the timing of cranial neural crest cell differentiation. The gene coding for histone H3 lysine 9 methyltransferase G9A was conditionally deleted in neural crest cells with Wnt1-Cre. The majority of homozygous-null animals survived to birth but thereafter failed to thrive. Phenotypic analysis of postnatal animals revealed that the mutants displayed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28644763
DOI: 10.1177/0022034517716438

Genes

RUNX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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