Article
Whole genome profiling of spontaneous and chemically induced mutations in Toxoplasma gondii.
BMC genomics - 10 May 2014
Farrell Andrew, Coleman Bradley I, Benenati Brian, Brown Kevin M, Blader Ira J, Marth Gabor T, Gubbels Marc-Jan
Abstract excerpt
BACKGROUND: Next generation sequencing is helping to overcome limitations in organisms less accessible to classical or reverse genetic methods by facilitating whole genome mutational analysis studies. One traditionally intractable group, the Apicomplexa, contains several important pathogenic protozoan parasites, including the Plasmodium species that cause malaria.Here we apply whole genome analysis methods to the...
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