Article
A replication study confirms the association of GWAS-identified SNPs at MICB and PLCE1 in Thai patients with dengue shock syndrome.
BMC medical genetics - 17 May 2014
Dang Tran Ngoc, Naka Izumi, Sa-Ngasang Areerat, Anantapreecha Surapee, Chanama Sumalee, Wichukchinda Nuanjun, Sawanpanyalert Pathom, Patarapotikul Jintana, Tsuchiya Naoyuki, Ohashi Jun
Abstract excerpt
BACKGROUND: Dengue shock syndrome (DSS), a severe life-threatening form of dengue infection, mostly occurs in children. A recent genome wide association study (GWAS) identified two SNPs, rs3132468 of major histocompatibility complex class I polypeptide-related sequence B (MICB) and rs3765524 of phospholipase C, epsilon 1 (PLCE1), associated with DSS in Vietnamese children. In this study, to examine whether an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
