Article
Host genetics and dengue fever.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2017
Xavier-Carvalho Caroline, Cardoso Cynthia Chester, de Souza Kehdy Fernanda, Pacheco Antonio Guilherme, Moraes Milton Ozório
Abstract excerpt
Dengue is a major worldwide problem in tropical and subtropical areas; it is caused by four different viral serotypes, and it can manifest as asymptomatic, mild, or severe. Many factors interact to determine the severity of the disease, including the genetic profile of the infected patient. However, the mechanisms that lead to severe disease and eventually death have not been determined, and a great challenge is...
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