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Article

Genetic variants of MICB and PLCE1 and associations with non-severe dengue.

PloS one - 1 Jan 2013

Whitehorn James, Chau Tran Nguyen Bich, Nguyet Nguyen Minh, Kien Duong Thi Hue, Quyen Nguyen Than Ha, Trung Dinh The, Pang Junxiong, Wills Bridget, Van Vinh Chau Nguyen, Farrar Jeremy, Hibberd Martin L, Khor Chiea Chuen, Simmons Cameron P

Abstract excerpt

BACKGROUND: A recent genome-wide association study (GWAS) identified susceptibility loci for dengue shock syndrome (DSS) at MICB rs3132468 and PLCE1 rs3740360. The aim of this study was to define the extent to which MICB (rs3132468) and PLCE1 (rs3740360) were associated with less severe clinical phenotypes of pediatric and adult dengue. METHODS: 3961 laboratory-confirmed dengue cases and 5968 controls were...

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Source

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Identifiers

PMID: 23536857
DOI: 10.1371/journal.pone.0059067
PMCID: PMC3594159

Genes

MICB
PLCE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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