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Article

Genetic association study of interferon lambda 3, CD27, and human leukocyte antigen-DPB1 with dengue severity in Thailand.

BMC infectious diseases - 11 Dec 2020

Arayasongsak Unchana, Naka Izumi, Ohashi Jun, Patarapotikul Jintana, Nuchnoi Pornlada, Kalambaheti Thareerat, Sa-Ngasang Areerat, Chanama Sumalee, Chaorattanakawee Suwanna

Abstract excerpt

BACKGROUND: Dengue patients develop different disease severity ranging from mild (dengue fever [DF]) to severe forms (dengue hemorrhagic fever [DHF] and the fatal dengue shock syndrome [DSS]). Host genetics are considered to be one factor responsible for the severity of dengue outcomes. To identify genes associated with dengue severity that have not been studied yet, we performed genetic association analyses of...

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PMID: 33308178
DOI: 10.1186/s12879-020-05636-w
PMCID: PMC7731073

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