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Article

Genetic variants of MICB and PLCE1 and associations with the laboratory features of dengue.

BMC infectious diseases - 9 Jun 2017

Whitehorn James, Kien Duong Thi Hue, Quyen Nguyen Than Ha, Wills Bridget, Van Vinh Chau Nguyen, Tam Dong Thi Hoai, Tuan Nguyen Minh, Jaenisch Thomas, Hibberd Martin, Khor Chiea Chuen, Simmons Cameron P

Abstract excerpt

BACKGROUND: A previous genome-wide association study identified 2 susceptibility loci for severe dengue at MICB rs3132468 and PLCE1 rs3740360 and further work showed these mutations to be also associated with less severe clinical presentations. The aim of this study was to determine if these specific loci were associated with laboratory features of dengue that correlate with clinical severity with the aim of...

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Identifiers

PMID: 28599625
DOI: 10.1186/s12879-017-2514-6
PMCID: PMC5466782

Genes

MICB
PLCE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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