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Article

Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.

Journal of the American Society of Nephrology : JASN - 1 Dec 2014

Chung Sharon A, Brown Elizabeth E, Williams Adrienne H, Ramos Paula S, Berthier Celine C, Bhangale Tushar, Alarcon-Riquelme Marta E, Behrens Timothy W, Criswell Lindsey A, Graham Deborah Cunninghame, Demirci F Yesim, Edberg Jeffrey C, Gaffney Patrick M, Harley John B, Jacob Chaim O, Kamboh M Ilyas, Kelly Jennifer A, Manzi Susan, Moser-Sivils Kathy L, Russell Laurie P, Petri Michelle, Tsao Betty P, Vyse Tim J, Zidovetzki Raphael, Kretzler Matthias, Kimberly Robert P, Freedman Barry I, Graham Robert R, Langefeld Carl D

Abstract excerpt

Lupus nephritis is a manifestation of SLE resulting from glomerular immune complex deposition and inflammation. Lupus nephritis demonstrates familial aggregation and accounts for significant morbidity and mortality. We completed a meta-analysis of three genome-wide association studies of SLE to identify lupus nephritis-predisposing loci. Through genotyping and imputation, >1.6 million markers were assessed in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24925725
DOI: 10.1681/ASN.2013050446
PMCID: PMC4243339

Genes

PDGFRA
GSX2
HAS2
SNTB1

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