Article
Differential Ly6C Expression after Renal Ischemia-Reperfusion Identifies Unique Macrophage Populations.
Journal of the American Society of Nephrology : JASN - 1 Jan 2016
Clements Meghan, Gershenovich Michael, Chaber Christopher, Campos-Rivera Juanita, Du Pan, Zhang Mindy, Ledbetter Steve, Zuk Anna
Abstract excerpt
Macrophages are a heterogeneous cell type implicated in injury, repair, and fibrosis after AKI, but the macrophage population associated with each phase is unclear. In this study, we used a renal bilateral ischemia-reperfusion injury mouse model to identify unique monocyte/macrophage populations by differential expression of Ly6C in CD11b(+) cells and to define the function of these cells in the pathophysiology...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
