Article
Macrophages in renal disease.
Journal of the American Society of Nephrology : JASN - 1 Jan 2011
Wang Yiping, Harris David C H
Abstract excerpt
Macrophages have heterogeneous phenotypes as they exercise their twofold role in the development and recovery of renal diseases. Some subpopulations of macrophages (M1) have a pathogenic function in renal inflammation, making them a logical target for elimination. Alternatively, M2 macrophage subpopulations resolve inflammation and repair injury, making them a potential therapeutic tool against renal injury....
Topics
- Animals
- Cell Proliferation
- Cell- and Tissue-Based Therapy
- Humans
- Kidney Diseases
- Macrophages
- Mice
- Models, Animal
- Nephritis
- Phenotype