Article
Phenotypic Characterization of Macrophages from Rat Kidney by Flow Cytometry.
Journal of visualized experiments : JoVE - 18 Oct 2016
Rubio-Navarro Alfonso, Guerrero-Hue Melania, Martín-Fernandez Beatriz, Cortegano Isabel, Olivares-Alvaro Elena, de Las Heras Natalia, Alía Mario, de Andrés Belén, Gaspar María Luisa, Egido Jesús, Moreno Juan Antonio
Abstract excerpt
There is increasing evidence suggesting the important role of inflammation and, subsequently, macrophages in the development and progression of renal disease. Macrophages are heterogeneous cells that have been implicated in kidney injury. Macrophages may be classified into two different phenotypes: classically activated macrophages (M1 macrophages), that release pro-inflammatory cytokines and promote fibrosis;...
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