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Article

The costs of being male: are there sex-specific effects of uniparental mitochondrial inheritance?

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 5 Jul 2014

Beekman Madeleine, Dowling Damian K, Aanen Duur K

Abstract excerpt

Eukaryotic cells typically contain numerous mitochondria, each with multiple copies of their own genome, the mtDNA. Uniparental transmission of mitochondria, usually via the mother, prevents the mixing of mtDNA from different individuals. While on the one hand, this should resolve the potential for selection for fast-replicating mtDNA variants that reduce organismal fitness, maternal inheritance will, in theory,...

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Identifiers

PMID: 24864311
DOI: 10.1098/rstb.2013.0440
PMCID: PMC4032517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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