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Article

Mitochondria, maternal inheritance, and male aging.

Current biology : CB - 25 Sept 2012

Camus M Florencia, Clancy David J, Dowling Damian K

Abstract excerpt

The maternal transmission of mitochondrial genomes invokes a sex-specific selective sieve, whereby mutations in mitochondrial DNA can only respond to selection acting directly on females. In theory, this enables male-harming mutations to accumulate in mitochondrial genomes when these same mutations are neutral, beneficial, or only slightly deleterious in their effects on females. Ultimately, this evolutionary...

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PMID: 22863313
DOI: 10.1016/j.cub.2012.07.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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