Article
Keeping mtDNA in shape between generations.
PLoS genetics - 1 Oct 2014
Stewart James B, Larsson Nils-Göran
Abstract excerpt
Since the unexpected discovery that mitochondria contain their own distinct DNA molecules, studies of the mitochondrial DNA (mtDNA) have yielded many surprises. In animals, transmission of the mtDNA genome is explicitly non-Mendelian, with a very high number of genome copies being inherited from the mother after a drastic bottleneck. Recent work has begun to uncover the molecular details of this unusual mode of...
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