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Article

Maternal inheritance of mitochondria: implications for male fertility?

Reproduction (Cambridge, England) - 1 Apr 2018

Vaught R C, Dowling D K

Abstract excerpt

Evolutionary theory predicts maternal inheritance of the mitochondria will lead to the accumulation of mutations in the mitochondrial DNA (mtDNA) that impair male fertility, but leave females unaffected. The hypothesis has been referred to as 'Mother's Curse'. There are many examples of mtDNA mutations or haplotypes, in humans and other metazoans, associated with decreases in sperm performance, but seemingly few...

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PMID: 29581388
DOI: 10.1530/REP-17-0600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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