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Article

Mitochondria, maternal inheritance, and asymmetric fitness: why males die younger.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Feb 2013

Wolff Jonci N, Gemmell Neil J

Abstract excerpt

Mitochondrial function is achieved through the cooperative interaction of two genomes: one nuclear (nuDNA) and the other mitochondrial (mtDNA). The unusual transmission of mtDNA, predominantly maternal without recombination is predicted to affect the fitness of male offspring. Recent research suggests the strong sexual dimorphism in aging is one such fitness consequence. The uniparental inheritance of mtDNA...

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Identifiers

PMID: 23281153
DOI: 10.1002/bies.201200141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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