Article
A broadly reactive monoclonal antibody detects multiple genotypes of hepatitis B virus X protein.
Archives of virology - 1 Oct 2014
Wei Lili, Shen Zhongliang, Zhao Xue, Wu Yanxin, Liu Wei, Zhang Junqi, Xie Youhua, Liu Jing
Abstract excerpt
A highly specific and broadly reactive monoclonal antibody against hepatitis B virus X (HBx) protein was developed that detected, in both immunoblotting and immunofluorescence, HBx proteins of seven of the eight currently known genotypes of HBV, which were overexpressed in cultured cells. Evaluation of HBx expression levels in cultured hepatocytes using this monoclonal antibody showed that cells transiently and...
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