Article
Transgenic mice expressing hepatitis B virus X protein are more susceptible to carcinogen induced hepatocarcinogenesis.
Experimental and molecular pathology - 1 Feb 2004
Zhu Huanzhang, Wang Yun, Chen Jianquan, Cheng Guoxiang, Xue Jinglun
Abstract excerpt
The hepatitis B virus X (HBx) protein is thought to be implicated in the development of human hepatocellular carcinoma (HCC), but its exact function remains controversial. To investigate whether the expression of the HBx gene alone can induce HCC on an inbred C57BL/6 strain that displays a lower...
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