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Article

Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein.

The Journal of general virology - 1 Mar 2008

Owsianka Ania M, Tarr Alexander W, Keck Zhen-Yong, Li Ta-Kai, Witteveldt Jeroen, Adair Richard, Foung Steven K H, Ball Jonathan K, Patel Arvind H

Abstract excerpt

The humoral response to hepatitis C virus (HCV) may contribute to controlling infection. We previously isolated human monoclonal antibodies to conformational epitopes on the HCV E2 glycoprotein. Here, we report on their ability to inhibit infection by retroviral pseudoparticles incorporating a panel of full-length E1E2 clones representing the full spectrum of genotypes 1-6. We identified one antibody, CBH-5, that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18272755
DOI: 10.1099/vir.0.83386-0
PMCID: PMC2885755

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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