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Article

Hepatitis B virus X protein promotes cell migration by inducing matrix metalloproteinase-3.

Journal of hepatology - 1 Apr 2005

Yu Feng-Ling, Liu Hung-Jen, Lee Jeng-Woei, Liao Ming-Huei, Shih Wen-Ling

Abstract excerpt

BACKGROUND/AIMS: Hepatitis B virus (HBV), a major causative agent of hepatocellular carcinoma (HCC), encodes an oncogenic X protein (HBx) that transcriptionally activates multiple viral and cellular promoters. How this regulation influences HCC is unclear. METHODS: Global gene expression in HBx-expressing and non-expressing hepatoma cells was analyzed using cDNA microarrays. RESULTS: Genes that were markedly up-...

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Identifiers

PMID: 15763339
DOI: 10.1016/j.jhep.2004.11.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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