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Article

Metabolomics analysis uncovers that dietary restriction buffers metabolic changes associated with aging in Caenorhabditis elegans.

Journal of proteome research - 6 Jun 2014

Pontoizeau Clément, Mouchiroud Laurent, Molin Laurent, Mergoud-Dit-Lamarche Adeline, Dallière Nicolas, Toulhoat Pierre, Elena-Herrmann Bénédicte, Solari Florence

Abstract excerpt

Dietary restriction (DR) is one of the most universal means of extending lifespan. Yet, whether and how DR specifically affects the metabolic changes associated with aging is essentially unknown. Here, we present a comprehensive and unbiased picture of the metabolic variations that take place with age at the whole organism level in Caenorhabditis elegans by using (1)H high-resolution magic-angle spinning (HR-MAS)...

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Identifiers

PMID: 24819046
DOI: 10.1021/pr5000686
PMCID: PMC4059273

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PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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