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Article

Metabolic profiling strategy of Caenorhabditis elegans by whole-organism nuclear magnetic resonance.

Journal of proteome research - 1 May 2009

Blaise Benjamin J, Giacomotto Jean, Triba Mohamed N, Toulhoat Pierre, Piotto Martial, Emsley Lyndon, Ségalat Laurent, Dumas Marc-Emmanuel, Elena Bénédicte

Abstract excerpt

In this study, we present a methodology for metabotyping of C. elegans using 1H high resolution magic angle spinning (HRMAS) whole-organism nuclear magnetic resonance (NMR). We demonstrate and characterize the robustness of our metabolic phenotyping method, discriminating wild-type N2 from mutant sod-1(tm776) animals, with the latter being an otherwise silent mutation, and we identify and quantify several...

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PMID: 19267476
DOI: 10.1021/pr900012d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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