Article
Distinct metabolic alterations in different Caenorhabditis elegans mitochondrial mutants.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences - 1 Aug 2021
Long Nguyen Phuoc, Kim Hyung Min
Abstract excerpt
Mitochondria play an essential role in various biochemical processes that maintain cellular homeostasis. Minor defects in the mitochondrial genome can lead to aversive behavioral responses in an organism. Nevertheless, little is known about the impact of mitochondrial mutations on the metabolome of Caenorhabditis elegans (C. elegans). In this study, an untargeted metabolomics approach was employed to elucidate...
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