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Article

Metabotyping of Caenorhabditis elegans and their culture media revealed unique metabolic phenotypes associated to amino acid deficiency and insulin-like signaling.

Journal of proteome research - 4 Mar 2011

Martin Francois-Pierre J, Spanier Britta, Collino Sebastiano, Montoliu Ivan, Kolmeder Carolin, Giesbertz Pieter, Affolter Michael, Kussmann Martin, Daniel Hannelore, Kochhar Sunil, Rezzi Serge

Abstract excerpt

Insulin/IGF-like signaling (IIS) and nutrient sensing are among the most potent regulators of health status and aging. Here, a global view of the metabolic changes in C. elegans with impaired function of IIS represented by daf-2 and daf-16 and the intestinal di- and tripeptide transport pept-1 wa...

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PMID: 21275419
DOI: 10.1021/pr100703a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21275419-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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