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Article

Metabolic Youth in Middle Age: Predicting Aging in Caenorhabditis elegans Using Metabolomics.

Journal of proteome research - 6 Nov 2015

Davies Sarah K, Bundy Jacob G, Leroi Armand M

Abstract excerpt

Many mutations and allelic variants are known that influence the rate at which animals age, but when in life do such variants diverge from normal patterns of aging? Is this divergence visible in their physiologies? To investigate these questions, we have used (1)H NMR spectroscopy to study how the metabolome of the nematode Caenorhabditis elegans changes as it grows older. We identify a series of metabolic...

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PMID: 26381038
DOI: 10.1021/acs.jproteome.5b00442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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