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Article

Evaluating the association of single-nucleotide polymorphisms with tenofovir exposure in a diverse prospective cohort of women living with HIV.

The pharmacogenomics journal - 1 Apr 2018

Baxi S M, Greenblatt R M, Bacchetti P, Cohen M, DeHovitz J A, Anastos K, Gange S J, Young M A, Aouizerat B E

Abstract excerpt

Higher exposure to tenofovir (TFV) increases the risk for kidney function decline, but the impact of genetic factors on TFV exposure is largely unknown. We investigated whether single-nucleotide polymorphisms (SNPs, n=211) in 12 genes are potentially involved in TFV exposure. Participants (n=91) from the Women's Interagency HIV Study, underwent a 24 h intensive pharmacokinetic sampling of TFV after witnessed dose...

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Identifiers

PMID: 28462920
DOI: 10.1038/tpj.2017.3
PMCID: PMC7793629

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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