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Article

The role of LRRK2 in the regulation of monocyte adhesion to endothelial cells.

Journal of molecular neuroscience : MN - 1 Jan 2015

Hongge Li, Kexin Guo, Xiaojie Mou, Nian Xiong, Jinsha Huang

Abstract excerpt

The leucine-rich repeat kinase 2 (LRRK2) gene was discovered to encode a member of an evolutionarily conserved family of proteins marked by GTPase domains usually in combination with kinase domains. Missense mutations in both the kinase and GTPase domains in LRRK2 have been found to cause late-onset Parkinson's disease (PD). In this study, we investigated the effects of the LRRK2 on endothelial inflammation. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24788225
DOI: 10.1007/s12031-014-0312-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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