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Article

An emerging role for LRRK2 in the immune system.

Biochemical Society transactions - 1 Oct 2012

Dzamko Nicolas, Halliday Glenda M

Abstract excerpt

Missense mutations in LRRK2 (leucine-rich repeat kinase 2) contribute significantly to autosomal dominant PD (Parkinson's disease). Genome-wide association studies have suggested further that mutations in LRRK2 comprise a risk factor for sporadic PD. How LRRK2 contributes to PD, however, is largely unknown. Recent work has shown that LRRK2 is highly expressed in tissue and circulating immune cells and is...

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Source

Identifiers

PMID: 22988878
DOI: 10.1042/BST20120119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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