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Article

Reduced folate carrier A80G polymorphism and susceptibility to neural tube defects: a meta-analysis.

Gene - 1 Dec 2012

Wang Hai-Gang, Wang Jia-Li, Zhang Jian, Zhao Li-Xia, Zhai Guang-Xi, Xiang Yu-Zhu, Chang Ping

Abstract excerpt

The reduced folate carrier (RFC1) plays a crucial role in mediating folate delivery into a variety of cells. RFC1 polymorphism (A80G) has been reported to be associated with increased risk of neural tube defects (NTDs). However, results derived from individually underpowered studies are conflicting. We performed a systematic search of MEDLINE and EMBASE databases and carried out a meta-analysis on the association...

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Identifiers

PMID: 22975209
DOI: 10.1016/j.gene.2012.02.020

Genes

RFC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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