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Article

RFC-1 80G>A polymorphism in case-mother/control-mother dyads is associated with risk of nephroblastoma and neuroblastoma.

Genetic testing and molecular biomarkers - 1 Feb 2015

Montalvão-de-Azevedo Rafaela, Vasconcelos Gisele M, Vargas Fernando R, Thuler Luiz Claudio, Pombo-de-Oliveira Maria S, de Camargo Beatriz

Abstract excerpt

AIM: Embryonic tumors are associated with an interruption during normal organ development; they may be related to disturbances in the folate pathway involved in DNA synthesis, methylation, and repair. Prenatal supplementation with folic acid is associated with a decreased risk of neuroblastoma, brain tumors, retinoblastoma, and nephroblastoma. The aim of this study was to investigate the association between MTHFR...

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Source

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Identifiers

PMID: 25536437
DOI: 10.1089/gtmb.2014.0177
PMCID: PMC4313402

Genes

MTHFR

Variants

rs1801133
rs1801133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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