Article
Absence of correlation between serum CRP levels and mitochondrial D-loop DNA mutations in gastro-oesophageal adenocarcinoma.
Journal of cancer research and therapeutics - 1 Jan 2000
Tan Benjamin H L, Skipworth Richard J E, Wheelhouse Nicholas M, Fearon Kenneth C H, Ross James A
Abstract excerpt
INTRODUCTION: Both inflammation and mitochondrial DNA (mtDNA) mutation are thought to play a role in the many human cancers. The aim of this study was to evaluate the relationship between inflammation and accumulation of mitochondrial DNA (mtDNA) mutations in the D-loop region in carcinogenesis of gastro-oesophageal adenocarcinomas. MATERIALS AND METHODS: Blood samples of 20 patients with gastro-oesophageal...
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