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Article

Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: a biomarker for the early detection of cancer.

Molecular cancer - 13 Dec 2006

Sui Guoping, Zhou Shaoyu, Wang Jean, Canto Marcia, Lee Edward E, Eshleman James R, Montgomery Elizabeth A, Sidransky David, Califano Joseph A, Maitra Anirban

Abstract excerpt

BACKGROUND: Somatic mutations of mitochondrial DNA (mtDNA) are common in many human cancers. We have described an oligonucleotide microarray ("MitoChip") for rapid sequencing of the entire mitochondrial genome (Zhou et al, J Mol Diagn 2006), facilitating the analysis of mtDNA mutations in preneop...

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Identifiers

PMID: 17166268
DOI: 10.1186/1476-4598-5-73
PMCID: PMC1764424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17166268-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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